Stereoselective Thiosulfonylation of Alkynes Using Sodium Thiosulfate as a Sulfur Transfer Agent to Access Bis-(Z)-Vinyl Sulfones

Key Points

• To explore sodium thiosulfate’s potential as a sulfur transfer agent for thiosulfonylation reactions.
• Utilized sodium thiosulfate in reactions with alkynes.
• Evaluated the formation of bis-(Z)-vinyl sulfones.
• Assessed the reaction conditions for optimal stereoselectivity.
• Sodium thiosulfate successfully acted as a sulfur donor in the reaction.
• Bis-(Z)-vinyl sulfones were synthesized with high stereoselectivity.
• The procedure demonstrated low environmental impact due to the green nature of the reactants.