儿童新发1型糖尿病中反复低血糖作为不寻常发现：病例报告及文献综述

Key Points

• This report aims to describe the unusual presentation of recurrent hypoglycemia in a child with new-onset type 1 diabetes and review existing literature on the topic.
• Case report of a pediatric patient showing recurrent fasting hypoglycemia and postprandial hyperglycemia at T1D onset.
• Clinical assessment included glucagon, glycated hemoglobin, and C-peptide levels.
• A narrative review was conducted via PubMed to identify literature on hypoglycemia at T1D onset prior to insulin initiation.
• The patient exhibited elevated glucagon levels (66–93 pmol/L) and high glycated hemoglobin (98 mmol/mol).
• C-peptide levels were low (0.05 nmol/L), suggesting impaired insulin production.
• Literature review identified several instances of recurrent hypoglycemia in children with new-onset T1D before insulin therapy.