Are S100A7 protein and V-set and immunoglobulin domain–containing 4 specific and robust early markers of severe acute pancreatitis? Authors’ rep | Synapse
February 28, 2026Open Access
Are S100A7 protein and V-set and immunoglobulin domain–containing 4 specific and robust early markers of severe acute pancreatitis? Authors’ rep
Key Points
The aim is to evaluate whether S100A7 protein and V-set and immunoglobulin domain–containing 4 can serve as early markers of severe acute pancreatitis.
Assessment of S100A7 protein and V-set and immunoglobulin domain–containing 4 levels
Comparison of markers in patients with and without severe acute pancreatitis
Analysis of marker specificity and robustness
S100A7 protein and V-set and immunoglobulin domain–containing 4 levels were significantly elevated in severe cases.
These markers demonstrated high specificity for early detection of severe acute pancreatitis.
Abstract
DOI: 10.20452/pamw.17239, Published online: February 26, 2026, Authors: Maciej Suski1,2, Paulina Dumnicka3, Mateusz Sporek4,5, Rafał Olszanecki1, Beata Kuśnierz-Cabala3