Condensation of previously synthesized 1,4-benzodioxane-2-carboxylic acid hydrazide with chloranhydrides of various arylcycloalkane-, as well as aerylterrahydropyrancarboxylic acids substituted in the aromatic ring, gave N,N′-diacyl-substituted hydrazines, which are cyclized under the action of phosphorus oxychloride to the corresponding 1,3,4-oxadiazolebenzodioxanes. The antihypoxic properties of the synthesized compounds were studied.
S. O. Vartanyan (2025) studied this question.