The Roche cTnT immunoassay detects both intact and degraded forms of cardiac troponin T, which degrades in a time-dependent manner following acute myocardial infarction.
These results demonstrate that the Roche cTnT immunoassay detects intact as well as degraded cTnT forms in AMI patients' sera during the period of diagnostic testing. Moreover, following AMI, cTnT is degraded in a time-dependent pattern.
Cardinaels et al. (Thu,) studied this question.