Effect of Adding Human Umbilical Cord Mesenchymal Stem Cells-Derived Secretome on Sperm Quality Improvement by Swim-Up Method.

Key Points

• This study examines how adding secretome from human umbilical cord mesenchymal stem cells affects sperm quality.
• Utilized the swim-up method for sperm selection.
• Administered human umbilical cord mesenchymal stem cells-derived secretome to sperm samples.
• Evaluated sperm motility and DNA fragmentation rates.
• Secretome increased rapid progressive motility of sperm.
• DNA fragmentation rates decreased significantly.
• Sperm concentration remained unaffected.