This meta-analysis indicates that MAP, DBP, SBP, SCr, triglyceride, 24-h UPE, LDL-C, male sex (vs. female), C4, hypertension, C-lesions, M-lesions, S-lesions, and T-lesions in Oxford classification are significantly associated with an increased risk of IgAN progression. In contrast, higher levels of Alb, eGFR, Hb, C3, as well as female sex (both as an independent variable and compared with males), are identified as protective factors in patients with IgAN.
Xu et al. (Sun,) studied this question.