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Integrating hybrid modeling and high throughput screening: A modular process development platform for flowthrough chromatography | Synapse
March 3, 2026
Integrating hybrid modeling and high throughput screening: A modular process development platform for flowthrough chromatography
LM
Llian Mabardi
University of Virginia
JR
J. Sri Ram
University of Virginia
CG
Chris A Gerberich
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Key Points
Enhanced process development in flowthrough chromatography is achieved through modular integration, and this improves efficiency.
High throughput screening methods allow for rapid evaluation of multiple parameters, which aids in optimizing processes.
The study utilizes hybrid modeling techniques to streamline bioprocess workflows and reduce development time significantly.
The findings suggest that integrating these methods may lead to cost-effective production and increased scalability.
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Mabardi et al. (Sat,) studied this question.
synapsesocial.com/papers/69a759ecc6e9836116a1f514
https://doi.org/https://doi.org/10.1016/j.chroma.2026.466715