Teneurin-4 in the nucleus accumbens modulates affective-like behaviors with potential effects on astrocytes in male mice

Key Points

• Affective-like behaviors demonstrate significant modulation influenced by teneurin-4 levels.
• Changes in behaviors were observed following specific interventions targeting nucleus accumbens pathways.
• Assessment using behavioral analysis in male mice showed noteworthy alterations in response to teneurin-4 manipulation.
• Understanding teneurin-4's role may lead to new insights on emotional regulation, especially concerning astrocytes.