Danggui Buxue Decoction and its active components alleviate COPD tracheal injury by regulating JAK-STAT pathway and glutathione metabolism in Drosophila and rats

Key Points

• Active components reduce tracheal injury and promote recovery in COPD models.
• Key metrics show significant improvements in lung function and oxidative stress markers in rats.
• Observational analysis involving both Drosophila and rat models highlights the role of glutathione metabolism.
• Indicates potential for new therapeutic strategies in treating COPD-related injuries in humans.