Novel hydrazone-derived pyrazole-benzofuran compounds inhibit cancer cell growth by targeting MMPs, caspases, and PI3K/AKT/mTOR signaling pathway

Key Points

• Compounds effectively inhibit cancer cell growth by targeting multiple signaling pathways.
• MMPs and caspases play crucial roles in the mechanisms of cell death, indicating their importance in treatment.
• Observational analysis of hydrazone-derived pyrazole-benzofuran compounds revealed their effects on cancer cells.
• These findings suggest new strategies for cancer treatment, but further validation is necessary.