Hydrogen-bond-assisted configurational diversity of benzamidines: experimental and theoretical study

Key Points

• The dynamic interconversion shows that benzamidines adopt various isomer configurations, enhancing their molecular complexity.
• NMR spectroscopic studies identify all four isomers, E-anti, E-syn, Z-anti, and Z-syn, demonstrating significant solvent effects.
• Analysis reveals some isomers can undergo linear or cyclic dimerization under certain conditions, impacting their interactions.
• The findings highlight the configurational diversity of benzamidines, suggesting implications for their chemical properties and applications.