Pretangle tau pathology accrual in the default mode network during the progression of Alzheimer’s disease

Key Points

• Increased tau pathology indicates rapid neurodegeneration in the default mode network of Alzheimer’s disease.
• The study identified significant tau accumulation over time, emphasizing its role in disease progression.
• Assessment through imaging techniques highlighted changes in neural networks associated with tau pathology.
• These findings underscore the importance of tau as a biomarker in tracking Alzheimer's disease evolution.