Exploring curcumin and its synthetic derivatives against key genes for therapeutics of rheumatoid arthritis in the Indian population: a computational approach

Key Points

• Curcumin and its synthetic derivatives show potential effects on key genes in rheumatoid arthritis treatments.
• Key genes targeted include those linked to inflammation, which are crucial for understanding disease mechanisms.
• This computational analysis assessed interactions among curcumin compounds and genes involved in rheumatoid arthritis.
• Findings highlight the need for further experimental validation before clinical application of these derivatives.