circSH3GL3 inhibits glioma progression and invasion via regulating the PI3K/AKT and Wnt/β-catenin signaling pathways by competitively binding with miR-21-5p

Key Points

• Inhibition of glioma progression is linked to the regulation of the PI3K/AKT and Wnt/β-catenin pathways.
• Key evidence shows that higher circSH3GL3 levels correspond to significantly reduced invasion rates in glioma cells.
• This analysis utilizes competitive binding assays to assess the interaction between circSH3GL3 and miR-21-5p.
• The findings suggest that targeting circSH3GL3 may offer new strategies for glioma treatment.