Metastatic Cutaneous Adnexal Carcinoma of the Head and Neck With Durable Response to an Aromatase Inhibitor Combined With a Cyclin‐Dependent Kinase 4/6 Inhibitor

Key Points

• A durable response was observed in a patient with metastatic cutaneous adenocarcinoma after treatment.
• Hormonal therapy combined with a cdk4/6 inhibitor proved effective, marking a notable success in this rare cancer.
• Routine immunohistochemical assessment of hormone receptors is essential for cutaneous adenocarcinomas in the head and neck region.
• The case highlights the potential of targeted therapies in managing challenging cancer cases.