Optimization of phenolic content and antioxidant activity from freeze- and microwave-dried Aegle marmelos seeds using ultrasound-assisted extraction and response surface methodology

Key Points

• Antioxidant activity increased significantly after optimization, nearing optimal levels during extraction.
• Phenolic content reached up to 25.6 mg GAE/g using ultrasound-assisted extraction and microwave-drying.
• Response surface methodology was utilized to refine extraction parameters, enhancing both yield and activity.
• Findings support using advanced extraction methods to maximize functionality in natural products.