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March 3, 2026
Roseburia intestinalis Offers Vagus-Dependent Neuroprotection Against Parkinson’s Disease
ML
Mengyun Li
JW
Jie Ying Wu
JX
Junjie Xiang
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Key Points
Neuroprotection is linked to roseburia intestinalis activity, suggesting a gut-brain connection.
Findings reveal significant vagus nerve involvement as a protective mechanism against parkinson's disease.
Assessment using animal models shows that gut microbiota plays a crucial role in neuroprotection processes.
These results highlight potential avenues for developing gut-targeted therapies for neurological diseases.
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Li et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75bebc6e9836116a241ea
https://doi.org/https://doi.org/10.1007/s12035-026-05707-0
罗丝布里亚肠道菌群对帕金森病提供迷走神经依赖的神经保护 | Synapse