The possible mechanism of L-arginine improved intestinal barrier health in grass carp (Ctenopharyngodon idella): via suppressing apoptosis and enhancing mitochondria-endoplasmic reticulum crosstalk

Key Points

• Intestinal barrier health improved significantly with L-arginine treatment, reducing cell death among grass carp.
• The study showed an increase in mitochondrial-endoplasmic reticulum crosstalk, crucial for cellular health.
• Apoptosis suppression was closely linked to enhanced gut integrity post L-arginine administration, indicating a protective effect.
• The findings highlight the potential of L-arginine in aquaculture, warranting further investigation in larger populations.