Association of NLRP3 (rs10754558, rs3806268, rs12137901) and ABCG2 (rs2231142) Gene Polymorphisms in Gout Susceptibility Among Asian and Caucasian Populations: A Meta-Analysis

Key Points

• Gout susceptibility is associated with NLRP3 and ABCG2 gene polymorphisms.
• Meta-analysis examines rs10754558, rs3806268, rs12137901, and rs2231142 from multiple populations.
• Analysis combines data from different ethnic groups to strengthen findings about genetic influence on gout.
• Findings support a genetic predisposition to gout, indicating the need for further studies across diverse populations.