Secretion-based production of prolyl-hydroxylated human type III collagen in scalable Physcomitrella photobioreactors

Key Points

• Collagen production is achieved efficiently in scalable photobioreactors, improving accessibility.
• The system produces prolyl-hydroxylated type III collagen, crucial for tissue engineering applications.
• Observational analysis encompassed various conditions within the Physcomitrella bioprocess.
• These findings highlight the potential for using moss systems in biotechnology and regenerative medicine.