Comparison of Laser Doppler Flowmetry With Contrast‐Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey ( Chlorocebus aethiops sabaeus ) | Synapse
March 3, 2026Open Access
Comparison of Laser Doppler Flowmetry With Contrast‐Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey ( Chlorocebus aethiops sabaeus )
Key Points
Discordant results were observed between laser doppler flowmetry and contrast-enhanced ultrasound regarding placental perfusion.
Specifically, laser doppler flowmetry proved unsuitable for measuring microvascular blood flow in a heterogeneous organ like the placenta.
This assessment involved using advanced imaging techniques to study blood flow in the placenta of African green monkeys over a defined period.
The findings highlight potential limitations of using LDF in complex biological structures, indicating a need for better methodologies.
Abstract
LDF and CEUS produce discordant results with respect to placental perfusion. LDF is ill-suited to a heterogeneous organ such as the placenta.