March 3, 2026Open Access

Comparative Efficacy of Ticagrelor and Clopidogrel in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: A Cardiac Magnetic Resonance Imaging-Based Pilot Study.

Key Points

Ticagrelor and clopidogrel showed similar outcomes on myocardial injury in patients.
The study focused on ST-elevation myocardial infarction patients undergoing PCI.

Structured PICO

Does ticagrelor improve CMR-based myocardial injury and long-term outcomes compared to clopidogrel in STEMI patients undergoing primary PCI?

Population

ST-Elevation Myocardial Infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI)

Intervention

Ticagrelor

Comparator

Clopidogrel

Outcome

CMR-based myocardial injury and long-term outcomessurrogate

In a pilot study of STEMI patients undergoing primary PCI, ticagrelor and clopidogrel demonstrated similar effects on CMR-based myocardial injury, providing feasibility data for future multicenter trials.

Abstract

Ticagrelor and clopidogrel showed similar effects on CMR-based myocardial injury and long-term outcomes in STEMI patients undergoing PCI. These pilot findings are hypothesis-generating and support the feasibility and inform sample-size planning for future multicenter trials.

Comparative Efficacy of Ticagrelor and Clopidogrel in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: A Cardiac Magnetic Resonance Imaging-Based Pilot Study.

Key Points

Structured PICO

Abstract

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