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Low necessity, high overuse: revisiting empirical vancomycin practices for children in low MRSA prevalence settings | Synapse
March 3, 2026
Open Access
Low necessity, high overuse: revisiting empirical vancomycin practices for children in low MRSA prevalence settings
PN
Phuwakrit Nithirungruang
Ramathibodi Hospital
CT
Chonnamet Techasaensiri
Mahidol University
SB
Sophida Boonsathorn
Mahidol University
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Key Points
Treatment with vancomycin may be excessive in children due to low MRSA prevalence, leading to potential risks of antibiotic resistance.
The study indicates that vancomycin was prescribed more than necessary, often in cases where alternative therapies would suffice.
Analysis of antibiotic prescribing patterns shows a misalignment with current treatment guidelines in pediatric care.
Highlights the importance of updating clinical practices to reduce unnecessary antibiotic usage in children.
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Nithirungruang et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75cfbc6e9836116a264ed
https://doi.org/https://doi.org/10.1186/s12879-026-12685-0