PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 3, 2026Bone0 citationsOpen Access

Site-specific inverse associations between FGF23 levels and marrow adiposity content at the proximal femur in post-menopausal women

View Full Paper
PJPaccou JulienBSBadr SammyRNRamdane Nassima

Key Points

  • Higher levels of cFGF23 and iFGF23 correlate with lower proximal femur PDFF, particularly at the femoral neck.
  • The study measured adiposity at specific sites, including the proximal femur and lumbar spine, finding site-specific relationships.
  • Observational analysis focused on post-menopausal women and their proximal femur adipose content.
  • These findings suggest that FGF23 may play a role in regulating marrow adiposity, but additional research is needed.

Abstract

An inverse association was found between cFGF23, iFGF23, and proximal femur PDFF (particularly femoral neck PDFF), but not with lumbar spine PDFF. Moreover, cFGF23 and iFGF23 levels were not associated with other adipose deposits.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Julien et al. (2026) studied this question.

synapsesocial.com/papers/69a75d12c6e9836116a26811https://doi.org/10.1016/j.bone.2026.117813
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulation of Phosphate Homeostasis by PTH, Vitamin D, and FGF232010 · 739 citations
  2. 2Gender differences in the association between anemia and osteoporosis: findings from a large-scale prospective analysis2024 · 5 citations
  3. 3Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production2015 · 497 citations
  4. 4Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla2008 · 392 citations
  5. 5The Multifaceted Roles of Bone Marrow Adipocytes in Bone and Hematopoietic Homeostasis2023 · 29 citations