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LSD1 maintains oocyte quality by epigenetically repressing CAMK2β to control granulosa cell-oocyte communication | Synapse
March 3, 2026
Open Access
LSD1 maintains oocyte quality by epigenetically repressing CAMK2β to control granulosa cell-oocyte communication
JZ
Jixian Zhang
Guiyang Medical University
YY
Yuanyuan Yu
Guiyang Medical University
ZZ
Zijian Zhu
Harbin University
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Key Points
Oocyte quality is maintained by LSD1, specifically through its epigenetic repression of CAMK2β.
The repression of CAMK2β enhances communication between granulosa cells and oocytes during folliculogenesis.
Assessment involved techniques in molecular biology to understand the interactions between LSD1 and CAMK2β.
Supporting oocyte quality through LSD1 may have implications for improving fertility treatments.
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Cite This Study
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Zhang et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d44c6e9836116a26ff9
https://doi.org/https://doi.org/10.1186/s12967-026-07730-0