Investigation of safety and efficacy of ZnO nanoparticle-loaded alginate-hyaluronic acid hydrogel for wound dressings: In vitro and in vivo studies

Key Points

• ZnO nanoparticles enhanced wound healing efficiency compared to non-loaded hydrogels.
• In vivo tests indicated significant improvement in wound closure rates within two weeks.
• Analysis of alginate-hyaluronic acid hydrogel showed biocompatibility in laboratory settings.
• Results may enable broader use of ZnO nanoparticle-loaded hydrogels in healthcare for better woundcare.