Effect of melatonin enriched with L-Tryptophan and 5-Hydroxytryptophan on sleep parameters in children with neurodevelopmental disorders

Key Points

• Improved sleep parameters were observed, enhancing overall sleep quality for affected children.
• The analysis showed significant changes in sleep duration and latency associated with melatonin treatment.
• Assessment using melatonin enriched with l-tryptophan and 5-hydroxytryptophan assessed sleep parameters for neurodevelopmental disorders.
• These findings may indicate a new therapeutic option for managing sleep issues in neurodevelopmental contexts.