Discriminative compensatory activation during auditory beat perception in Parkinson’s disease and multiple system atrophy

Key Points

• Compensatory mechanisms differ between Parkinson's disease and multiple system atrophy regarding auditory beat perception.
• In Parkinson's disease, cerebellar activation is primarily observed, whereas the premotor cortex is activated in multiple system atrophy.
• The findings provide insights into how RAS therapy could be adapted to better suit individual patients' needs.
• These distinct compensatory patterns highlight the importance of understanding brain activation in atypical parkinsonian disorders.