Impact of whole breast irradiation, endocrine therapy or their combination on outcomes of early-stage, luminal A-like, low-risk, breast cancer patients aged 65 years or over: Insights from the EUSOMA database

Key Points

• Irradiation and endocrine therapy affect outcomes in older breast cancer patients, promoting better management strategies.
• In EUSOMA's dataset, patients aged 65 and older showed varied responses to treatment combinations, indicating personalized care needs.
• Analysis of treatment pathways for luminal A-like, low-risk breast cancer highlights the complexity in clinical decision-making.
• Findings may enable tailored therapeutic approaches for older patients, improving survival and quality of life.