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Patterns of cognitive and motor decline in Alzheimer’s Disease (AD) and ageing in healthy populations | Synapse
March 3, 2026
Open Access
Patterns of cognitive and motor decline in Alzheimer’s Disease (AD) and ageing in healthy populations
MB
Maddalena Beccherle
SA
Stefania Amato
EF
Elena Facci
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Key Points
Cognitive decline is observed alongside motor decline in Alzheimer's Disease, implying a shared pathway in neurodegeneration.
Key evidence includes significant impairment metrics where Alzheimer's participants show a 40% greater decline in cognitive functions.
Analysis through longitudinal studies helps identify trends in cognitive and motor decline across various age groups.
This highlights the importance of early intervention strategies targeting brain health and motor functions in older adults.
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Beccherle et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75f47c6e9836116a2a8bb
https://doi.org/https://doi.org/10.1007/s40520-026-03327-1
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