“Host-guest induced” enhanced electrochemiluminescence from tb (III)-doped mixed-valence Ce-MOF for antibody well-orientation biosensing

Key Points

• Electrochemiluminescence improved significantly for biosensing purposes, enhancing detection efficiency.
• Key evidence shows a notable increase in luminescent response due to the host-guest induced effects of tb(III) ions.
• Using a mixed-valence cerium metal-organic framework (Ce-MOF), the orientation of antibodies was optimized for better performance.
• Implications include the potential for more sensitive biosensors, although additional validation is required for application in real-world settings.