Bioactive Sphingosine from Ficus racemosa: Isolation, Structural Elucidation, DFT Studies and Cytotoxic Potential against Oral Carcinoma Cells Via in Vitro and in Silico Approaches

Key Points

• Bioactive sphingosine shows significant cytotoxic potential against oral carcinoma cells, indicating possible therapeutic use.
• Cytotoxicity was assessed through various in vitro assays, revealing these cells are particularly sensitive to sphingosine.
• DFT studies were utilized to establish the structural elucidation of sphingosine, clarifying its molecular characteristics.
• The findings highlight the need for further exploration of bioactive compounds in cancer treatment strategies.