March 3, 2026Journal of Oral Biosciences1 citationsOpen Access

Identification of Mfa5-2 as a structural component of Mfa1 fimbriae in Porphyromonas gingivalis

NMNaoyoshi MiwaAichi Gakuin University MHMakoto HirohataAichi Gakuin University YYYui YoshimuraAichi Gakuin University

Key Points

Mfa5-2 is a newly identified structural component of Mfa1 fimbriae in Porphyromonas gingivalis.
The study highlights the structural diversity of Mfa1 fimbriae, suggesting complex assembly mechanisms.
Assessment focused on the expression of Mfa5-2, a high-molecular-weight component in two strains of P. gingivalis.
Findings offer insights that may enhance understanding of pathogenic mechanisms in Porphyromonas gingivalis.

Abstract

Mfa5-2 is expressed as a high-molecular-weight component and integrated into the Mfa1 fimbriae in P. gingivalis EM3 and 1439. These findings revealed previously unknown structural diversity of Mfa1 fimbriae.

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Cite This Study

Miwa et al. (Sun,) studied this question.

synapsesocial.com/papers/69a76073c6e9836116a2d379 https://doi.org/https://doi.org/10.1016/j.job.2026.100753

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