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Outcomes of Geriatric Patients Receiving CD19 Directed CAR-T Therapy: A Single Institution Study | Synapse
March 3, 2026
Outcomes of Geriatric Patients Receiving CD19 Directed CAR-T Therapy: A Single Institution Study
RT
Riya Tandra
Temple University Hospital
CD
Christina C Darwish
Temple University Health System
NB
Nicholas Barnaba
Temple University Hospital
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Key Points
Geriatric patients receiving CD19 directed CAR-T therapy showed positive clinical outcomes, enhancing treatment options.
In this study, overall survival rates improved, with 70% of patients achieving a significant response.
Assessment involved retrospective data analysis from a single institution, focusing on patient characteristics and treatment responses.
This highlights the importance of exploring CAR-T therapy in older adults, a population often underrepresented in clinical trials.
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Tandra et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760a7c6e9836116a2d9a8
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.687