Allogeneic Hematopoietic Cell Transplantation for Infantile Osteopetrosis: High Rates of Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease (SOS/VOD) and Transplant-Related Morbidity | Synapse
March 3, 2026
Allogeneic Hematopoietic Cell Transplantation for Infantile Osteopetrosis: High Rates of Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease (SOS/VOD) and Transplant-Related Morbidity
Key Points
High rates of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) were observed post-transplant.
Approximately 60% of infants experienced transplant-related morbidity after hematopoietic cell transplantation.
Assessment included infants diagnosed with osteopetrosis and their post-transplant outcomes.
This highlights the need for careful monitoring and management of complications during treatment.