Adaptation of iNKT Cell Expansion Protocol for Clinical Use in a GVHD Prevention Trial

Key Points

• iNKT cell expansion may reduce the incidence of graft versus host disease (GVHD), improving transplant outcomes.
• The adaptation of the expansion protocol was designed for use in clinical settings, enhancing patient safety and efficacy.
• Analysis involved an initial evaluation of the protocol across multiple transplant centers, focusing on its practical application.
• Further investigation is necessary to establish long-term efficacy and safety in preventing GVHD effectively.