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Impact of Obesity on GVHD Following Post-Transplantation Cyclophosphamide in Patients Undergoing Allogeneic Hematopoietic Cell Transplant | Synapse
March 3, 2026
Transplantation and Cellular Therapy
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肥胖对接受异体造血干细胞移植后环磷酰胺治疗的GVHD影响
NA
Naveed J. Ali
Fred Hutch Cancer Center
AH
Alycia Hatashima
University of Washington
XF
Xinyi Fan
Fred Hutch Cancer Center
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Key Points
肥胖显著提高了移植后移植物抗宿主病(GVHD)的风险。
体重指数较高的患者在移植后可能会经历更严重的免疫反应。
通过涉及多个中心和患者记录的详细调查评估揭示了结果中的关键模式。
这突出了在预测移植患者GVHD时考虑肥胖的重要性。
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Ali等(Sun)研究了这个问题。
synapsesocial.com/papers/69a760dfc6e9836116a2e078
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.668