Optimization of hyaluronic acid production from Bacillus subtilis strain PV154141.1in submerged fermentation

Key Points

• Hyaluronic acid production increases with optimized conditions, reaching significant yield improvements.
• Yield enhanced by 35% through adjusting fermentation parameters such as pH and temperature.
• Observational analysis of metabolic pathways in Bacillus subtilis during submerged fermentation.
• Highlights importance of optimizing fermentation for biopolymer production, indicating industrial applications.