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YTH Domain Family 2 Promotes Tubal Factor Infertility through Reducing H3K4me1 Methylation of CYLD by KMT2D | Synapse
March 3, 2026
YTH Domain Family 2 Promotes Tubal Factor Infertility through Reducing H3K4me1 Methylation of CYLD by KMT2D
LS
Liang Shao
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
NW
Nansu Wang
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
YY
Yan Yan
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
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Key Points
Tubal factor infertility is influenced by YTH domain family 2's regulation of H3K4me1 methylation.
A reduction in the methylation of CYLD was closely linked to infertility pathways, highlighting genetic impacts.
The analysis utilized a molecular approach to examine methylation patterns in relevant infertility pathways.
This research suggests potential avenues for novel infertility treatments connected to methylation alterations.
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Cite This Study
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Shao et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76140c6e9836116a2f03f
https://doi.org/https://doi.org/10.1007/s12010-026-05582-4