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Targeting the lipid membrane to prevent viral entry: the case of a C18-alkylated EGCG compound | Synapse
March 3, 2026
Targeting the lipid membrane to prevent viral entry: the case of a C18-alkylated EGCG compound
CM
Cristina Minnelli
Marche Polytechnic University
SC
Sara Caucci
RG
Roberta Galeazzi
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Key Points
Viral entry is significantly reduced using the C18-alkylated compound, affecting membrane integrity.
The study shows a 70% reduction in viral binding with the EGCG compound across multiple trials.
Analysis employs in vitro techniques to assess the impact of the compound on lipid membranes.
Highlights potential for lipid-targeting strategies in developing antiviral treatments.
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Minnelli et al. (Sat,) studied this question.
synapsesocial.com/papers/69a7615dc6e9836116a2f37d
https://doi.org/https://doi.org/10.1016/j.cbi.2026.111971