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Manganese acts as savior rather than accomplice of antibiotic stress: Dual cycles of ROS scavenging and Mnammox | Synapse
March 3, 2026
Manganese acts as savior rather than accomplice of antibiotic stress: Dual cycles of ROS scavenging and Mnammox
DH
Dong-Jun Hou
Hangzhou Normal University
WG
Weilin Guo
Hangzhou Normal University
QL
Qian-Ru Liu
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Key Points
Manganese significantly reduces oxidative stress from antibiotics, acting as a savior rather than a contributor.
ROS scavenging and Mnammox cycles demonstrate a dual mechanism for manganese's protective function.
Analysis of manganese's interaction with antibiotic stress highlights its unexpected beneficial role in mitigating damage.
Findings suggest manganese contributes positively to antibiotic stress responses, pointing to therapeutic potential.
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Hou et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76166c6e9836116a2f4ae
https://doi.org/https://doi.org/10.1016/j.jwpe.2026.109678