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Intramuscular droperidol, olanzapine, midazolam, or lorazepam to treat methamphetamine intoxication in the emergency department | Synapse
March 3, 2026
Intramuscular droperidol, olanzapine, midazolam, or lorazepam to treat methamphetamine intoxication in the emergency department
JC
Jon B. Cole
Hennepin County
PD
Paige A. DeVries
JO
Jamie L. O'Flaherty
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Key Points
Intramuscular droperidol, olanzapine, midazolam, or lorazepam proved effective in treating methamphetamine intoxication.
Midazolam exhibited significant efficacy, showing improvements in symptoms for the majority of cases within 30 minutes.
Observational analysis compared four medications administered intramuscularly, exploring their individual effects on intoxicated patients.
Findings highlight the need for standardized protocols in emergency settings for treating methamphetamine intoxication.
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Cole et al. (Wed,) studied this question.
synapsesocial.com/papers/69a761cec6e9836116a2fe2a
https://doi.org/https://doi.org/10.1016/j.ajem.2026.02.027
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