Predictive Relations Between Early Adversity, Nonlinear Trajectories of Hypothalamic–Pituitary–Adrenal Axis Functioning, and Later Callous-Unemotional Traits

Key Points

• Callous-unemotional traits are predicted by nonlinear trajectories of hypothalamic-pituitary-adrenal axis functioning.
• Individuals facing early adversity show significant variations in HPA axis functioning, influencing emotional traits.
• Observational analysis highlights the importance of early experiences in shaping psychological development and traits.
• Understanding these predictive relations may help in designing interventions for emotional and behavioral problems.