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K92 Lactylation of YBX1 orchestrates m5C RNA recognition to facilitate colorectal Cancer progression | Synapse
March 3, 2026
K92 Lactylation of YBX1 orchestrates m5C RNA recognition to facilitate colorectal Cancer progression
SC
Siche Chen
Heidelberg University
XW
Xinyu Wang
YC
Yanbin Chen
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Key Points
YBX1 lactylation significantly enhances m5C RNA recognition, facilitating tumor progression.
The study highlights a key molecular mechanism in colorectal cancer, implicating lactylation in disease advancement.
The analysis routes through the lactylation pathway, linking it specifically to YBX1 and its RNA interactions.
Supporting colorectal cancer studies, this groundwork may lead to new biomarker targets for intervention.
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Chen et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76563badf0bb9e87d8eb9
https://doi.org/https://doi.org/10.1016/j.ijbiomac.2026.150686