Synthesis, In-silico and In-vivo anticonvulsant activity of substituted 2-Phenyl Indole derivatives

Key Points

• Significant anticonvulsant activity observed in in-vivo models, suggesting therapeutic potential.
• In-silico studies predict favorable interactions of 2-phenyl indole derivatives with target receptors.
• Assessment involved both computational and experimental approaches to evaluate efficacy and safety.
• Findings imply these derivatives could lead to new treatments for epilepsy.