Integrated omics-based analysis reveals the role of ferulic acid activating a co-production of 4-vinyl guaiacol and fumaric acid by Rhizopus oryzae

Key Points

• Ferulic acid activates the co-production of 4-vinyl guaiacol and fumaric acid.
• Increased levels of 4-vinyl guaiacol and fumaric acid highlight product yield.
• Integrated omics-based analysis on Rhizopus oryzae was utilized to characterize the process.
• Findings may enable optimized bioprocessing strategies for metabolite production.