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Anti-Shigella activity and killing kinetics of compounds from MMV Pathogen and COVID Boxes: Identifying leads against Shigellosis | Synapse
March 3, 2026
Open Access
Anti-Shigella activity and killing kinetics of compounds from MMV Pathogen and COVID Boxes: Identifying leads against Shigellosis
LY
Lauve Rachel Tchokouaha Yamthe
FM
Francine Kengne Mediesse
Ministry of Scientific Research and Innovation
YD
Yanick Kevin Melogmo Dongmo
Université de Yaoundé I
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Key Points
Compounds exhibit anti-Shigella activity, targeting the pathogen effectively for treatment.
The study reveals distinct killing kinetics, helping to understand how quickly the compounds work.
Assessment involves screening compounds from MMV Pathogen and COVID Boxes to identify potential leads.
This work supports the need for new treatments against shigellosis, a significant public health concern.
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Yamthe et al. (Thu,) studied this question.
synapsesocial.com/papers/69a7661bbadf0bb9e87dbb6f
https://doi.org/https://doi.org/10.1016/j.crphar.2026.100251