Genetic Landscape and Linkage Analysis of Factor VIII Gene Markers in Indian Women: Improving Carrier Detection for Haemophilia A

Key Points

• Carrier detection for haemophilia A can be improved using genetic markers related to factor VIII.
• Analysis conducted on the genetic landscape of factor VIII gene markers specifically in Indian women.
• Linkage analysis illustrates significant relationships between certain markers and haemophilia A inheritance.
• Findings may enhance screening methods for healthy carriers, facilitating better management of haemophilia A.