Differentiation of mesenchymal stem/stromal cells into CD45+ macrophage-like cells: expanding insights into MSC plasticity

Key Points

• Macrophage-like cells can arise from mesenchymal stem cells, highlighting their plasticity.
• Key findings include increased CD45 expression during differentiation, indicating immune characteristics.
• This work employs a differentiation approach to analyze mesenchymal stem cell plasticity and immune response.
• Findings suggest further exploration in therapeutics and immune modulation using plasticity of stem cells.